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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8283217f3ecdbb524105240c2cdd445fd5ce5bdaf7024f0dbafc1d6fb9ea3509' 
  AND token = 'dEvsf0q/aduyy3Mft6Hm5cJxjRzuLLGBNwqe0xHvO8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}