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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9d3378c48e975200009135a2b0d65e2fcef5e057513e97425434be8d6f2ee3b' 
  AND token = '7dnFGGMH9ypsDPuEUsSSeY1eferUnVVhROrM9J4Zn+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}