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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58a7c68853c5cd3efd960fd1ad1b877b384c936b328b8cce30dd3bff8eba4294' 
  AND token = 'ntIcMS77FuYL+JDyL4F5F2bYreDJ1D5RDqUvsoIoIQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}