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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b89cd019c094f7bb9a440ffa12da7bb3ef2005c47d5b7d151ceab49e032c24e' 
  AND token = 'OLEUuKq0/Xu5rFRNKItXwyhrFZ5tqvzq5hcajhiV4kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}