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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '187df612cc1b738f2b58b503e844cb7bec30e8edb6b92f3394a775c5a1cf5977' 
  AND token = 'z+ZjqKbAXNdkve+McUAL+bOpY4y6FvheC4KfA0rL8EU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}