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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '476bad0078ac82ff6f112637d112ff6a2ed06b6a40af0f5330591077c0989648' 
  AND token = '2zvmAZv5/eCr1SYicJqoLWA9RD6CMz0Lttiw1iJ1LQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}