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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c180ad07b867cecf5913e4894fde0e7f9dd28e9b60e7dea5d43314787d9c408a' 
  AND token = 'r/eSbdnZrwjNXFnE3q3W+xeJjKHtyqegxOaaB8onJBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}