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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f81ea71e3060c9df6d3dc02f2f54bcdbb7031eb03b7f02e118b6e02c9b000695' 
  AND token = '1eSmnB+kO+ljD091KAPQmviLO7x/HvaIL8CB4oGNX/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}