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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8c676846bbc13225e25f4256553444bcc797ddbf8e0d2b0177f9ed11d8b87ff' 
  AND token = 'nu+54ddFXuz1aOJCiE16n58rogYDc64Xxlyua27/sf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}