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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0691c8ef615457bf79bc1933dfe171e40dbd952fc306d5d40b7d44405be32cd5' 
  AND token = 'XYv7ycC5rAP0l2PcJlEpzwX++LsMemRd3A1aDHa9bbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}