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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80a9251e316fa50b4ebcd788eeb8e91d6c95ff8801ca9b897614a197868d98cb' 
  AND token = 'l5WGjZy4HSMrcW+F3dkrEcdK72a0PJbub9F290pkBYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}