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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f12fbc8aa4d96b9a61812f624a93609afa01e66f7d4e289cbaee16e6060763' 
  AND token = 'jGGAu4gdyxCPI3a4Vf7EJTzfCMjWzF/RBlXFDt8KNGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}