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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5346c234356f68f0c8e305536ba2182127bf7711f81f3693c7168de269a4c46' 
  AND token = 'f2DZlhLEFipXK3UTSBS2XiBaqhxZTxQ784VeslJO6+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}