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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e68e608abd40cd0ef7622657e12e04592bd952554219dd8b38dc3449477c06c7' 
  AND token = 'p/VcbuUXf+EcuRxj8lcsmA63hp0bBFP5zoJQQ1ZlSR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}