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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3f8ba3c248f6a003eda0a73539c6999b157ba55ed0c39d293e18b89d340e80f' 
  AND token = 'tdXsjtwfS1xD12IBxK3jRMFPZYvC84WPykPxB6FDW7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}