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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea3dfaf611d624aede7fb3c14feb336499250a284f32913ed1c11d142179d21' 
  AND token = 'FOODi+qDc7BWS/g6c0iMK/C4SeSfM+AD63PFO2o8ayM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}