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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2daf71c827fe2aaa67119efa56cabf01936ea3151e0306478a94cd799b101116' 
  AND token = 't07vEsg/BAmhMUqr/JYo79pld24SdyHujDTAUwbDD/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}