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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '889e6188635805fdd639a6ea28db2425f60022e81808c9b9014f85f94f12e841' 
  AND token = 'EOkjnfqP9olNEg3+Cl8Bag4u7ETysvwim4kTTZB+Wx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}