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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a37d6de55cf24901c4584a5da295e232708cb4236c546be3b9893c4b08aa8fd' 
  AND token = '6ip4ahOxfG0HNHB8ToAP2ZgS7qtQTA+CF87VqEpRmAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}