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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd4145ee98176d4024e9f85c6f35511db0853a84feb4b52bab0ea7e0924f6a2a' 
  AND token = '2t+ejD0h9hOl+TZLcguCRoUzVjCZdMdU74docqFoW90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}