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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e90966f3d2d9b6e8ea453f287b5e60a91091a63268f12e74a06c2f9de0f29c4f' 
  AND token = '51QkNS3gsVAhrJQbAfgVgNSx2n6+Hb0CQH9Ev3aWosc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}