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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55f0a573ba07a9b4d8d107c4ac32090e18b6fe3441f9428fd49cef225e05f213' 
  AND token = '4iitbUDjcvbbsTAt0Ze1aHg0YlWJIp3I1vryzJKlPTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}