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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f2b3b6fbaa05b564f4eaf78e82dadb6061d133996d864665e452703e2eef3a9' 
  AND token = '1z/HtE22m0EhRpyRRvw9Q/ilH9zWON1qmtd6Qot024o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}