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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8e3d94f2d2923995e3848cc6a8edf43c5814f6386f30bbb5c96d621b0d3071f' 
  AND token = 'bv2zfUaZa0kJUBueTeJX9z7z489z6QSEixrKxhppSF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}