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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aef9ea02431b80b66e60344ce40c3981935b6077f89540f12dd4f72d53dd86f0' 
  AND token = 'T2Mj94m3a4pYwC8QnWSZgva65idADWvFe1iUSVko2Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}