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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f2ccb9b2711a3acb693d54e20d1139c53a832138f053d98f2b8287014c4d2c9' 
  AND token = 'HxmTk2jJLc21zJ36wz/vVfdkBLYkppCMALxbtz1kGME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}