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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eaab62cda68378148c1f02e961050335b6c6fd21cd4fa8df8564021ca3fa592' 
  AND token = 'cMjmXFTblcu2Z21O/katEMCjrM1JJecEBvUYxeGUl+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}