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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d321d7ae877ce98403384e7b9b3f6d953801d7b79cee0d2d75b49e2d32bbfa' 
  AND token = 'SOT4+6jbvgQ5UughfYa0+X1dgyUK9R9KpX/Ae4mAfyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}