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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6951134d8563e88a53ac5c0030ff192e11ac8cdc3b66025ef03150d987f09bd5' 
  AND token = 'u0XnsWovzx4tyUx01hYig/jA8+U8qHB8LWuc5KUnN98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}