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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f27633a9d461b4e7d04fdf22f63583008ce1f63c48fac0ea4edb22f67f6f8f' 
  AND token = 'WhoO1VyfjVlV7H4SI4F1nlgO9moCgedMkzT+ckluQkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}