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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c5a0a1c648e88e6d0f1a462389de9c3020de0ee22c26f457aa06f1fbe7e2ceb' 
  AND token = '+0i2u1cxc4lhKxSqVTIdqZrny86MNvrBFtgGTf/Sl+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}