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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3d5e4b41998a026b9f654c0cc3839f7535dca04b6a8f34dd4d3236cda909880' 
  AND token = 'InnRl0VWbM6pSa2JTXrc7V7iz1dVbiLFy1uRc4K/T8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}