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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6408f5233898e2397f8db0dafd9b4fe514225a3242ec45b0bb3537fe3972b217' 
  AND token = 'FPq+jRGxG9C7urIjeyRYLJaX2P0yjuyphX8RUtK8u90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}