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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6885ff780c3fd4432762db36fdce7830370a0e43fbae3ecc6af0379fa490146' 
  AND token = '9e+37EWM0/Vqg3NAgBztYDOj33EMCAQ4jVywp1MkgxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}