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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '325bdfca7b3ad01212f80b8dc92d7162fae4f381933be89181b94183afca8924' 
  AND token = 'xCIolkQyOs1InNf0tjEYNOLx4q/AzgPdLuEL6eX+6ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}