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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e80850b35c22756b88c51ea3280baeca8398b305865711a2f01fdb64b9b283e' 
  AND token = 'Tp9HCxtSbBaVI5v/Fqz97LHUaZ3j+BnJbZz0Fgnvnc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}