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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a75893018a7a9cb54042321bd20c3725ceb6239477df0e6e9fc3c7c5ec6efe84' 
  AND token = '/Z4FexrUu1IDnXUnpB6AY2p6fKPxcTJV6eCxoIAvGVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}