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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '525ec8122d1b871c321f2200f169ed048d2ad655c360fa9b0094de2f600845c9' 
  AND token = 'Hn+Vqq0itdEC04ryTE5Ik2XTJByGy3GQER5ZXXz/XjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}