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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8917dcfe07c64e56d95629af581fca0b05f10538c5d77358e73381a0e85e5a98' 
  AND token = 'cQsh6UQ45INoOwLTc0ixA/w3GAj1ZKSBjdFUha6SN5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}