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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4a5ed4fc34645b1ed89569bc84b5d8868fd11e5b56517c37340e8b54825091' 
  AND token = 'T+0BXqmC2028cKnh8/Camf8Sz/CuuzwZ4QMmewwHPTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}