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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eb5dd53344f7621babb424f9d984c0e7e854dd7e2ec1054b84eafb9fd63d43a' 
  AND token = 'drW2SJPY1ozn6AVh2JiHlVKSjlnXo0aKmAkbCvxsTjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}