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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a17abb57928485836370cd4b57bc57635d6a77cad3ce122025a582f396238a6' 
  AND token = '3/HXKUf8sOLE5XXEp7o9/4TVCcdGsz4kKVPyxJPTIy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}