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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a1bb1e3df80afe8251692ab0508fd18d084c70768e95e51a9a9dfb70c71e566' 
  AND token = '+EdXm2PVcO3IVY+eYE5rz4+fvtIM3L2TzsjqTDPBEf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}