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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f46ed30b36c5b0f7aa955725f82f58b983f3aeb8c861cbde41007b879e741977' 
  AND token = 'gmGxivzm4/IPkkdN+nIicz2e4DbKnrxSAqf18ReLkUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}