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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b54d778243d479cf80d67c5d183897215955328bb98d4f2c9579c02daf9a6016' 
  AND token = 'QJMwNzOuavaMlIEmDMg9Kt2bFCoCFSWdVsYeFIm0y80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}