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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a4b288c6ad66065ef2ac3b31ed8afd0022e36df7751b143e443da85717f54c6' 
  AND token = 'tW6VHFEm6fdKvIO/BQL1jv28JHUME4HU/Bf7llyYJCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}