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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3cbf1b53c41023e423755b345bba4630c413704a9e53b2b9b8508c0c49a6998' 
  AND token = 'rnuNdxardTMpT+8AUH3dNguDF9dEghTl9BAD0s//LmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}