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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427aef1683e1926bab763f4a1da3a4cdf32a804f30ce4fc1ba14ab10b764ba71' 
  AND token = '33wkFFe5XAuoTsEc33ygtwrvO5RVBslz6b1vyMeSpe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}