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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40e16bbf2b54f91e064b9399fdc3955da8f5580613b00ffdb5ceecca3e2c1435' 
  AND token = 'earX4LcYkvv+wZ7kTvRf2WaA9r2uHO+mYBVociChbf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}