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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '472d3982dee4a78d56f4d987b38f37edf577427cd53b912089337eae97c2f542' 
  AND token = 'iEPuIE2RsmW+TnQ5m1zDsoKi4FJ/dCiVO4C399F1Wnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}